Rapid detection of H1N1 avian influenza virus detection is not reliable

Officials estimate that since early April there had been infected with H1N1 bird flu up to 1 million Americans a lot. Its symptoms, which is similar to the seasonal flu, which may include fever, headache, coughing, sneezing, sore throat, muscle or joint pain for up to one week. Who has been working with a considerable number of infected people also reported diarrhea and vomiting. Antiviral drugs such as Tamiflu and Relenza have been found effective treatment and reduce the duration of the disease, from one or two days in general. However, in order to play the biggest role, it must in the management of symptoms 12 to 48 hours. This may be a problem, taking into account the traditional identification of cell culture, the virus may take several days, and rapid detection tests can provide results within 30 minutes or less are not sure H1N1 virus, more than half the time, according to a new government report .

The U.S. Centers for Disease Control (CDC) for research and testing has proved to contain the use of laboratory testing, from the three companies: Binax Inc., Becton, Dickinson Company, and three Quidel’s influenza virus clinical samples Quidel best performance of the test and found that 69 percent of infections. In flow cytometry, Dickinson trial testing 49-fold, Binax test found that 40 percent. All tests found that seasonal influenza H1N1 viruses better than that. “These findings suggest that, despite the positive (rapid detection test) results can be made to deal with decisions, negative results do not exclude new influenza (H1N1) virus infection,” the author writes with.

These findings are not entirely unexpected. A clinical virology to a recent study found that a test found that only 10 percent of the H1N1 virus infection, and the second found that only 40%. In the “absence of a ton of rapid detection of influenza” can pick a more advanced laboratory culture, long?????Christensen said that in microbiology, virology and molecular diagnostics, director of the north shore of Long Island Jewish Medical System in Lake Success, while in New York, in a letter in June New England Journal of Medicine, the U.S. Navy researchers have described the Quidel tests of sensitivity, and noted that they found that only half of the infections picked up a more sensitive technology.

However, the test makers say their product is helpful, if used properly. Clinical and regulatory affairs senior vice president of Quidel Corporation John Tamerius said Quidel’s QuickVue influenza virus A-and B-type influenza antigen detection tests can be found 80 percent of infections, if the specimen from the management of the nose to do swabs taken directly to the self-correct, and if this test is given at an early stage disease, when more of the viral infection process. “When used properly these tests, performance is very, very good,” Tamerius said.

Last week, the Center for Disease Control and Prevention updated guidance, requiring careful examination to rely on fear of negative readings may prevent antiviral treated patients, especially those high-risk, such as pregnant women and those with asthma or other conditions of the basic medical health-care providers such as heart disease and diabetes.

By: jagat  :  Filed Under Alerts & Outbreaks

FDA’s Warning On Electronic Cigarettes

The U.S. Food and Drug Administration warned the U.S. not to use electronic cigarettes, because they contain cancer-causing chemicals, including one of the other toxins in the antifreeze compounds. However, they did not ban the sale of these smoke-free devices.

Cigarettes and other similar electronic products, online sales, as well as kiosks in shopping malls throughout the United States scores also. These devices can be a hot gas, feels like a real smoke nicotine spray. (Also nicotine, free version of the electronic cigarette.) Now, FDA has tested two of these devices: Njoy products and equipment of smoking everywhere.who is a lawyer, is also a director of FDA’s drug evaluation and research departments to adhere to the office, said: “Our product review so far, we have found to be illegal.” However, the U.S. FDA is still not carrying prohibited goods such equipment, because there is pending litigation on the FDA jurisdiction over the issue of electronic cigarette.

So why hold a press conference on the problem? Joshua Sharfstein, Ph.D., and FDA Principal Deputy Commissioner, said: “We think it is important, although there are lawsuits, we are considering the options, no one can right the U.S. FDA’s position on this issue causes confusion.”

At the news conference, an FDA analyst Benjamin Westenberger to describe test from the E, two brands of 19 different cartridges, the U.S. FDA facilities in St. Louis cigarettes. They found that, in these tests:
• All of the bullets, but was marked as a non-nicotine, whereas the actual substance of the addiction.
• that are considered to have low, medium, high, or the actual amount of nicotine in varying degrees of nicotine was significantly cartridges.
• The ink cartridges a positive, there is a toxic antifreeze ingredient, diethylene glycol.
• light-emitting device is a “tobacco-specific nitrosamines are carcinogenic.”
• The device is also suspected to have fired the tobacco specific impurities harmful to humans.
FDA’s press conference also features also issued strong opposition to the use of electronic cigarettes, some experts warn:
• Dr. Jonathan Weinikefu, who is the President of the Association of tobacco Pediatrics, American Academy of Sciences warned that these types of products seems to be specific, in order to have attractive children. He said that these devices can be nicotine addiction, children, eventually they are smoking.
• Dr. Matthew McKenna, who is the CDC’s Office on Smoking and Health pointed out that electronic cigarettes can also be in the environment is smoke-free, thereby weakening the anti-smoking efforts with health benefits.
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• Dr. Jonathan who is also a global health at the University of Southern California, director of the Institute warned that the e-cigarette nicotine is not the same, the delivery of the approval by the FDA in order to help people quit smoking equipment. He also pointed out that he has not confirmed the benefits of electronic cigarette, but the risk is also very clear.

Since 2008, the U.S. Food and Drug Administration has been trying to prevent their entry into the United States, e-cigarette. To date, approximately 50 volume of refuse, but has yet to stop sales and distribution of electronic cigarettes. In March 2009, Canada, a complete ban on the use of these devices.

Manufacturers and distributors of the E – cigarettes argue that their equipment safer than smoking real cigarettes, thus reducing the hazards of smoking. Some people even suggest that their products to help people quit smoking tobacco products.

FDA has rejected these demands, because these devices can provide synthesis of nicotine dose, without the approval of these agencies as they know the safety of drug delivery devices. It is also no evidence that these devices can safely help people stop smoking, but they have significant potential to attract them to the candy and fruit flavors, new smokers.

The electronic in many sizes and shapes to cigarettes. Many of them look like a long cigarette, while others can look like a pipe or cigars. They are still at work, basically the same way:
• User inhaled through a mouthpiece.
• Air Flow sensor is triggered, will open a small battery-powered heater.
• heater and then a small casket where evaporation of liquid nicotine, but also activate the light, in the “lit” end of the electronic cigarette. Users can also select a nicotine cartridge is free of charge.
• heater will also ink vaporization of propylene glycol (PEG). Polyethylene glycol is a stage in which the smoke from the elements.
• The user then get very close to the hot gas jet of tobacco smoke.
• When the user emitted, there is a polyethylene glycol vapor cloud looks like smoke. Steam will quickly dissipate.
• in the electronic cigarette contains no tobacco products. Even nicotine cigarettes are integrated in the electronics.
The device is usually retail for 100-200 yuan. The filled cartridge packaging different prices depending on nicotine. There are liquids to do it-yourself cartridge sales. Each cartridge is filled with several purposes.

The equipment manufacturers say they do not have health requirements for their products. Craig, Brad, who is InLife electronic cigarette company’s president, and pointed out that tobacco is bad for you because often, your non-smoking thing assuages nicotine habit, the need to reduce bad for you.

“In our product you have a nicotine or no nicotine, polyethylene glycol, and some seasoning. Your cigarette nicotine, polyethylene glycol, 4,000 chemicals and 43 carcinogens. My supporters or harm reduction. The people of have the right and choice, should be allowed to let them. ”

Others believe that, as a deceptive way to make people addicted to nicotine such equipment. One of them is that these people Michael Erickson, Ph.D., who is of public health in Atlanta, Georgia State University and the Center for Disease Control and Prevention Office of Smoking and Health, former director, director of the Institute.

“I do not see any evidence that people from tobacco cigarettes, electronic cigarettes or other smokeless tobacco products switch. If you look at how the market smokeless products, and their things, sometimes you can not smoke for sale. The implication is that you nicotine may increase rather than reduce smoking, “Eriksson said.

By: jagat  :  Filed Under Alerts & Outbreaks

Celiac disease poses the risk of death than previously expected

Most Americans do not stop to find out their favorite pizza or a delicious chocolate biscuits contain a protein called gluten, but celiac disease (CD) of people, this is a big problem. When a person who ate the food discs containing gluten, their immune system attacks the small intestine, intestinal villus damage, thus inhibiting the absorption of important nutrients and deprive vegetative. Left diagnosed and treated, the CD will lead to weight loss, anemia, osteoporosis, infertility, neurological problems and increased risk of cancer. Symptoms CD-ROM also increased mortality, 2 to 4 times the total population, but a new study shows that even if the potential or reduce the severity of the disease, at a higher risk of death.

To determine the CD will be different levels of personal risk of death, the researchers analyzed data from 46,121 cases in Sweden from July 1969 to February 2008, including in the small intestine biopsy biopsy data. In these patients, there are 29096 CD-ROM, while the 13306 and 3719 intestinal inflammation has a potential CD, they tested positive for blood diseases, antibodies, but the signs of intestinal inflammation or damage. The study, published in the Journal of the American Medical Association.

Patient follow-up of about 7 to 9 years in the median, in this period, 3049 people were killed and the CD, those between 2967 and inflammation between the potential CD group 183. When the data compared to the Swedish general population registers, records of all three groups compared with a matched control group, a higher risk of death, an increase of 35% with potential CD, 39% of the risk, an increase of with CD, risk, and an increase of 72 percent and the risk of inflammation.

The highest risk of death during the first year of follow-up to the potential associated with the 1.8 CD-ROM-fold increased risk of death, with the 2.8 CD – times, and to 4.7-fold increase in inflammation. After the first year of follow-up, these figures dropped. The risk of death with the age at diagnosis and risk, while the higher were diagnosed before the age of 20. “Finally, we found that increased (risk of death of the individual and the biopsy) authentication celiac disease, inflammation, celiac disease and the potential, but the absolute risk small. Personal experience in the small intestinal biopsy in children increased (mortality risk). Cardiovascular disease and Cancer is the leading cause of death caused by celiac disease, “the authors wrote.

Jonas Ludvigsson, the study’s main author, pediatrics professor at the University Hospital in Örebro, Sweden proposed to increase the mortality rate of several explanations, including “energy and vitamin inflammation and chronic malnutrition.” He said, high-risk and inflammation may be because they have not been told to follow a gluten-free diet, often leading to the normalization of the disease.

In an editorial, human resources Bideboshi green, celiac disease center at Columbia University School of Medicine and surgical director of the New York doctor, wrote that this study provides the risks associated with the CD key information to enhance the importance of diagnosis of the doctor disease. “Until recently, gluten sensitivity and has received documents the importance of traditional medicine, despite the existence of an increasing number of patients with various nervous system diseases and mental problems, evidence. Ludvigsson and colleagues from the research should be strengthened as a diagnosis by a doctor to seek the importance of celiac disease. The Committee also recommended that more attention should be given to intestinal inflammation and a lower degree of gluten sensitivity. ”

Strict compliance with a gluten-free diet remains the only treatment for this disease, it can be very vital wheat gluten, as you can from the breakfast cereals and meat to prepare lunches for the lipstick and skin care products can be challenging. Gluten intake in any form can trigger disc to become active.

By: jagat  :  Filed Under Disease & Illness

12 weird medical conditions

The current common diseases, people experience flu-like in their daily lives and in their daily world, such as cancer and heart disease to find a way of people’s lives. The medical profession has always had its hands full diagnostic and treatment methods. Although many diseases are still for their development and treatment of clues, some are so strange, different, they leave the medical profession confused.

ABC News medical unit, especially reporters and Dan Erzi, take the time to compile the most rare and most puzzling medical condition, 12 in recent years. There is no known treatment methods and treatment, because the conditions are very special, although the doctor in the case back to find the reasons for these strange symptoms and conditions.

Klippel-Trenaunay syndrome is one who finds himself from the more than one under the conditions found in the name of health care workers. Carla Sosenko, however, has been the public is most concerned about her syndrome is a rare congenital disease, resulting in excessive bone growth and body fat deposition in different parts of the abnormal results. But the real danger is in pain and blood clots, seizures threats, and blindness.

Another reason is that persistent impulse syndrome, it found a high tide line the edge of the victims often do not own wishes. Foreign accent syndrome like the plague Rosemary Dole, with whom different than her own accent in a stroke. Hereditary sensory and autonomic neuropathy is a condition so that people, mostly children, and feel no pain, which is particularly dangerous to allow any of the body did not say it happened because of the pain of it – sometimes self-induced injury -. Gabby Gingras, etc., an 8-year-old is one of the conditions suffered by children, and now she wore after losing her teeth and her own, because they can not distinguish between the correct physical injuries and protective equipment, eye care.

Other conditions have no names, because there are so doctors have yet to identify the problem in order to identify the causes of symptoms and a small number of cases. Christopher Sands is a 25-year-old who started in February 2007 hiccup, and has never completely stopped, because any action in a calm will eventually find it back. Natalie Adler has a condition in Australia, so that her eyes closed, rather than the next three days to open under any circumstances. And the song is prompted seizures, although her which part of the brain was removed to alleviate the conditions in a young woman filled with the world of music has not yet cure her tendency.

Some people were found to have a strange reaction to cold weather. Wei Muhe Lanhuo Fu has a cold, he has used in trying to get visibility and complete tasks such as climbing Mount Everest wearing shorts. According to the other side of this coin is that the patient suffering from cold urticaria, allergic reactions, skin conditions in patients with low-temperature lead and running the risk of seizures and shock reactions.

In the other conditions that include the American Broadcasting Corporation carried out in four-year-old boy named Rhett Lamb who can not sleep, although there have been carried out surgery on his brain, trying to remedy the deficiencies. Brad Williams, a 52-year-old who can not forget the moment of life experiences, but also the whole spectrum of memory as a grand mal inspection and immediate disappearance of the other side of people.

As it is rarely described, but can be very serious weakening of the victims and seriously inhibit their quality of life. To make matters worse, most of the medical profession are confused, often dedicated years of research to discover why certain conditions occur.

By: jagat  :  Filed Under Disease & Illness

U.S. cancer mortality continued to decline Show

Americans enjoy their risk of cancer deaths overall declined steadily. This is mainly due to improved methods of early diagnosis through screening, to improve cancer treatment, as well as the method of cancer prevention through. U.S. researchers said recently that in the past three decades, these factors have more significant declines in cancer mortality. The study, published in the journal Cancer Research.

According to Dr. Eric Scott Hailunweishi children in Grand Rapids, Michigan and hospital colleagues, all age groups there have been some improvements in cancer deaths. However, the age group that has experienced the most significant decline in cancer mortality, including 35-45 years of age young adults. Scott said: “In essence, the young person, you, the faster the rate is declining.”

Coulter pointed out, cancer prevention, including smoking cessation programs as the creation of such efforts, has been a key factor in improving cancer mortality. He further pointed out that “we have from our progress in early diagnosis and treatment benefit from a more profound way. These advances are beneficial to young people for the first time.” A good example can be seen for childhood cancer, treatment of the landmark achievements, such as leukemia, lymphoma, has enabled millions of people in order to survive what were previously regarded as incurable, fatal diseases known.

Other improvements include life-saving cancer detection has been implemented, such as the breast X-ray, methods, and colon cancer colonoscopy. These films have the ability to detect cancer at an early stage, when they are more easily cured.

Survey measured the decline in cancer death age. Scott’s team analysis of cancer mortality and from the World Health Organization statistical information system to obtain data on the population. The researchers examined cancer mortality rates by age and birth cohort dropped by 10-year period, beginning in 1925.

According to Scott, “Every person born in the 20th century, it had enjoyed since the age of 30 reduce the risk of cancer death in every era.” However, the most significant improvement in the study pointed out that the youngest age group 35 to 45 years , a 25.6 percent drop in cancer deaths is observed every 10 years. For older groups, was 6.8 per cent drop every 10 years, said.

Although the Government estimates indicate that only a slight improvement in cancer death, until the mid-1990s, the 20th century, Kort said that it did not give us a comprehensive understanding. In a telephone interview, he pointed out: “In these reports, statistics, the traditional approach is that their average age group with access to the composite interest rate.” He further explained that “with this is a problem, because most cancer deaths occurred The average weight of older persons in the United States stressed that the elderly experience. it. like to see the train caboose to tell when the train to change direction ”

According to the U.S. Center for Disease Control and prevention of cancer is the second leading cause of death of Americans, taking away lives of almost 560,000 per year. Heart disease remains the leading cause of death, more than 630,000 people were killed.

By: jagat  :  Filed Under Disease & Illness