Celiac disease poses the risk of death than previously expected

Most Americans do not stop to find out their favorite pizza or a delicious chocolate biscuits contain a protein called gluten, but celiac disease (CD) of people, this is a big problem. When a person who ate the food discs containing gluten, their immune system attacks the small intestine, intestinal villus damage, thus inhibiting the absorption of important nutrients and deprive vegetative. Left diagnosed and treated, the CD will lead to weight loss, anemia, osteoporosis, infertility, neurological problems and increased risk of cancer. Symptoms CD-ROM also increased mortality, 2 to 4 times the total population, but a new study shows that even if the potential or reduce the severity of the disease, at a higher risk of death.

To determine the CD will be different levels of personal risk of death, the researchers analyzed data from 46,121 cases in Sweden from July 1969 to February 2008, including in the small intestine biopsy biopsy data. In these patients, there are 29096 CD-ROM, while the 13306 and 3719 intestinal inflammation has a potential CD, they tested positive for blood diseases, antibodies, but the signs of intestinal inflammation or damage. The study, published in the Journal of the American Medical Association.

Patient follow-up of about 7 to 9 years in the median, in this period, 3049 people were killed and the CD, those between 2967 and inflammation between the potential CD group 183. When the data compared to the Swedish general population registers, records of all three groups compared with a matched control group, a higher risk of death, an increase of 35% with potential CD, 39% of the risk, an increase of with CD, risk, and an increase of 72 percent and the risk of inflammation.

The highest risk of death during the first year of follow-up to the potential associated with the 1.8 CD-ROM-fold increased risk of death, with the 2.8 CD – times, and to 4.7-fold increase in inflammation. After the first year of follow-up, these figures dropped. The risk of death with the age at diagnosis and risk, while the higher were diagnosed before the age of 20. “Finally, we found that increased (risk of death of the individual and the biopsy) authentication celiac disease, inflammation, celiac disease and the potential, but the absolute risk small. Personal experience in the small intestinal biopsy in children increased (mortality risk). Cardiovascular disease and Cancer is the leading cause of death caused by celiac disease, “the authors wrote.

Jonas Ludvigsson, the study’s main author, pediatrics professor at the University Hospital in Örebro, Sweden proposed to increase the mortality rate of several explanations, including “energy and vitamin inflammation and chronic malnutrition.” He said, high-risk and inflammation may be because they have not been told to follow a gluten-free diet, often leading to the normalization of the disease.

In an editorial, human resources Bideboshi green, celiac disease center at Columbia University School of Medicine and surgical director of the New York doctor, wrote that this study provides the risks associated with the CD key information to enhance the importance of diagnosis of the doctor disease. “Until recently, gluten sensitivity and has received documents the importance of traditional medicine, despite the existence of an increasing number of patients with various nervous system diseases and mental problems, evidence. Ludvigsson and colleagues from the research should be strengthened as a diagnosis by a doctor to seek the importance of celiac disease. The Committee also recommended that more attention should be given to intestinal inflammation and a lower degree of gluten sensitivity. ”

Strict compliance with a gluten-free diet remains the only treatment for this disease, it can be very vital wheat gluten, as you can from the breakfast cereals and meat to prepare lunches for the lipstick and skin care products can be challenging. Gluten intake in any form can trigger disc to become active.

Posted by: jagat  :  Category: Disease & Illness

4 Responses to “Celiac disease poses the risk of death than previously expected”

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